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Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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The first mobile photon-counting detector CT: the human images and technical performance study.

Su-Jin Park¹, Junyoung Park¹, Doil Kim¹

¹Health & Medical Equipment Business, Samsung Electronics Co., Ltd, 129, SamSung-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16677, Republic of Korea.

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Summary

Photon-counting-detector CT (PCD-CT) offers higher spatial resolution and multi-spectral imaging capabilities. This new technology demonstrates diagnostic equivalence to conventional scanners and enables advanced material decomposition for enhanced medical imaging.

Keywords:

PCD-CT human images photon-counting detector techincal performance

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Area of Science:

Medical Imaging
Radiology
Biomedical Engineering

Background:

Conventional energy-integrating detector CT (EID-CT) has limitations in spatial resolution and spectral information.
Photon-counting-detector CT (PCD-CT) technology offers potential advancements in image quality and quantitative analysis.
The mobile PCD-CT system (OmniTom Elite) has received FDA 510(k) clearance for clinical use.

Purpose of the Study:

To evaluate the human imaging capabilities of a mobile PCD-CT system.
To assess the 'on demand' higher spatial resolution and multi-spectral imaging features of PCD-CT.
To demonstrate the feasibility and performance of PCD-CT in clinical settings.

Main Methods:

Utilized an FDA-cleared mobile PCD-CT scanner (OmniTom Elite).
Imaged certified CT phantoms and a human cadaver head to assess high-resolution (HR) and multi-energy imaging.
Conducted first-in-human imaging on three volunteers to demonstrate clinical performance.

Main Results:

First human PCD-CT images at 5 mm slice thickness were diagnostically equivalent to conventional EID-CT.
PCD-CT HR mode achieved 11 lp/cm resolution, significantly higher than EID-CT's 7 lp/cm (standard mode).
Quantitative multi-energy CT performance showed accurate material decomposition (iodine, calcium, water) with low error (3.25% in VMI).

Conclusions:

PCD-CT enables multi-resolution acquisition without hardware changes, offering superior spatial resolution over conventional mobile EID-CT.
The quantitative spectral capability of PCD-CT allows for accurate, simultaneous multi-energy imaging for material decomposition and VMI generation.
PCD-CT represents a significant advancement in mobile CT technology, enhancing diagnostic capabilities and quantitative analysis.