Contributions to Mare Reproduction Research by the Ginther Team

Examples of research discoveries and first reports on mare reproduction by the O.J. Ginther team are (1) determined daily circulating concentrations of four hormones during the estrous cycle, (2) showed that mares can be induced to ovulate and superovulate by hormone treatment during both ovulatory and anovulatory seasons, (3) demonstrated that prostaglandin F2α was the luteolysin in mares, (4) described the mare's elaborate hormonal and biochemical mechanism for selecting the ovulatory follicle from a pool of like follicles, (5) developed the method for diagnosing fetal sex by Day 60 using location of the genital tubercle, (6) refuted the dogma that the primary corpus luteum regresses at about one month of pregnancy, (7) demonstrated that the uterus induces luteolysis in nonpregnant mares through a systemic pathway unlike the local uteroovarian venoarterial pathway in ruminants, (8) developed the method for greatly reducing the devastating twinning problem, and (9) discovered intrauterine embryo mobility and fixation and thereby solved several enigmas in mare reproduction. During 56 years on the University of Wisconsin faculty, Ginther was sole author of seven hard cover texts and reference books. He supervised 112 graduate-students, postdoctorates, and research trainees from 17 countries. His team published 680 full-length journal papers that were cited 43,034 times according to Google Scholar. The Institute for Scientific Information ranked him among the top 1% of the world's scientists in all fields. According to a survey in 2012-23 by Expertscape, he published more scientific manuscripts than anyone on ovarian follicles, corpora lutea, and luteolysis.