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Epigenetically programmed resistance to chemo- and immuno-therapies

Reddick R Walker1, Zainab Rentia2, Katherine B Chiappinelli1

  • 1The George Washington University Cancer Center (GWCC), Washington, DC, United States; Department of Microbiology, Immunology & Tropical Medicine, The George Washington University, Washington, DC, United States.

Advances in Cancer Research
|March 29, 2023
PubMed
Summary

Epigenetic alterations drive cancer growth and treatment resistance by changing gene expression. Targeting these epigenetic changes offers a promising strategy to overcome therapy resistance and improve cancer cures.

Keywords:
3D chromatinAcetylationCancerChemotherapyEpigeneticsHistone modificationsImmunotherapyMethylation

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