Novel vinegar solution for denture-cleansing agent

Area of Science:

• Oral Microbiology
• Biomaterials Science
• Antimicrobial Agents

Background:

• Denture stomatitis is a common oral condition.
• Biofilm formation on dentures contributes to oral health issues.

Purpose of the Study:

• To evaluate the antimicrobial and anti-biofilm efficacy of a novel vinegar-based denture cleansing agent.
• To assess its effects on oral Streptococci and Candida species.

Main Methods:

• Utilized time-kill assays and biofilm inhibition tests on denture bases.
• Tested against Streptococcus mutans, Streptococcus sobrinus, Streptococcus sanguinis, Candida albicans, and Candida glabrata.

Main Results:

• Vinegar demonstrated rapid antibacterial effects on Streptococci within 15 minutes.
• Significant reduction of Streptococci biofilm (6 log) achieved in 30 minutes.
• Anticandidal effects required longer treatment (3-6 hours) for significant reduction in planktonic cells and biofilm.

Conclusions:

• The novel vinegar-based cleanser exhibits moderate antibacterial properties.
• It effectively inhibits both bacterial and Candida biofilm formation on denture bases.
• Longer immersion times are needed for optimal anticandidal efficacy compared to conventional agents.