Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unmodified orientable osteoclastic cytomembrane bionic fluorescent magnetic nanocarbons as high-efficiency multifunctional platforms for antiresorptive compound discovery.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Advancing health equity in proactive health management: from data underrepresentation and algorithmic bias to a closed-loop governance framework.

Frontiers in public health·2026
Same author

Outcomes of donation after circulatory death heart transplant using normothermic regional perfusion: a systematic review and meta-analysis.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs·2026
Same author

Three-Dimensional Facial Aesthetic Analysis of Oval and Rectangular Face Shapes in Han Chinese Women for Plastic Surgery Applications.

The Journal of craniofacial surgery·2026
Same author

Cis and trans regulatory mechanisms of extrachromosomal DNA segregation.

Nature cell biology·2026
Same author

GALNT7 promotes the malignant progression of gastrointestinal stromal tumors by regulating KIT O-GalNAc glycosylation.

Precision clinical medicine·2026

Related Experiment Video

Updated: Aug 5, 2025

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

7.5K

Patient-Specific Implants for Correction of Midfacial Aging.

Xin Wang1, Xiaoping Chen2, Qiming Zhao1

  • 1Department of Plastic Surgery, Zhejiang Hospital Affiliated to the Zhejiang University School of Medicine.

The Journal of Craniofacial Surgery
|March 30, 2023
PubMed
Summary

Patient-specific implants (PSIs) customized using CAD/CAM effectively reduce nasolabial fold (NLF) depth caused by midfacial aging. This innovative approach significantly improves NLF appearance and patient satisfaction, offering a precise solution for aesthetic enhancement.

More Related Videos

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
08:15

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

6.5K
Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
05:54

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla

Published on: October 18, 2021

1.9K

Related Experiment Videos

Last Updated: Aug 5, 2025

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

7.5K
3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects
08:15

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

6.5K
Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
05:54

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla

Published on: October 18, 2021

1.9K

Area of Science:

  • Plastic Surgery
  • Biomedical Engineering
  • Aesthetic Medicine

Background:

  • Midfacial aging can lead to deepening of nasolabial folds (NLFs), affecting facial aesthetics.
  • Traditional augmentation methods may have limitations in achieving precise correction for NLFs.

Purpose of the Study:

  • To design and customize patient-specific implants (PSIs) using CAD/CAM for correcting NLF deepening.
  • To evaluate the efficacy and patient satisfaction with PSIs in shallowing NLFs due to midfacial aging.

Main Methods:

  • Utilized patient head CT data for 3D reconstruction and custom PSI design.
  • Employed CAD/CAM techniques for precise fabrication and implantation of PSIs into the nasal base.
  • Assessed NLF severity using wrinkle rating scales and overall aesthetic improvement via a global esthetic improvement scale.

Main Results:

  • All 11 patients (22 NLFs) showed reduced NLF severity post-surgery.
  • High precision and excellent fit of customized PSIs were observed.
  • Significant aesthetic improvement and high patient satisfaction were reported, with over 90% experiencing much or extremely improved NLFs (P < 0.01).

Conclusions:

  • Individualized PSIs, precisely designed with CAD and manufactured with CAM, offer a reliable solution for NLF correction.
  • This method overcomes limitations associated with non-customized implants.
  • Customized PSIs provide a stable, effective, and highly satisfactory treatment for age-related NLF deepening.