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Measuring intramolecular connectivity in long RNA molecules using two-dimensional DNA patch-probe arrays.

Timothy K Chiang, Ofer Kimchi, Herman K Dhaliwal

    Biorxiv : the Preprint Server for Biology
    |March 30, 2023
    PubMed
    Summary

    Researchers developed a patch-probe method to map RNA connections in vitro. This technique reveals RNA folding structures and how modifications like pseudouridine affect them.

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