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Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer's Disease
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Shared and disease-specific glial gene expression changes in neurodegenerative diseases
Nature Aging
|March 30, 2023
Abstract:
We found evolutionarily conserved astrocyte and microglia subpopulations shared across multiple brain regions. We reveal similarities and differences between Alzheimer's disease glia and Parkinson's disease glia, as well as regional variance linked to disease pathology and neurodegeneration.
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