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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

653
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Related Experiment Video

Updated: Aug 4, 2025

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Intraocular Lens Exchange: Indications, Comparative Outcomes by Technique, and Complications.

Veshesh Patel1, Parastou Pakravan1, James Lai1

  • 1Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine, Miami, FL, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|March 30, 2023
PubMed
Summary

Intraocular lens (IOL) exchange significantly improves vision and refractive outcomes. However, specific techniques carry risks, such as dislocation with iris-sutured IOLs and tilt with Yamane fixation.

Keywords:
Yamanecataractscomplicationsdislocationintraocular lenstechniques

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Area of Science:

  • Ophthalmology
  • Surgical Techniques
  • Patient Outcomes

Background:

  • Intraocular lens (IOL) exchange is a complex procedure.
  • Understanding the indications, outcomes, and complications is crucial for patient care.
  • Choosing the appropriate surgical technique impacts visual results and complication rates.

Purpose of the Study:

  • To describe the indications, outcomes, and complications of intraocular lens (IOL) exchange.
  • To determine the relative frequency of postoperative complications among different IOL exchange techniques.

Main Methods:

  • Retrospective analysis of 511 eyes undergoing IOL exchange from May 2014 to August 2020.
  • Evaluation of visual acuity, refractive outcomes, and complication rates.
  • Comparison of complication frequencies across various surgical techniques (iris-sutured, scleral-sutured, anterior chamber IOL, Yamane fixation).

Main Results:

  • Mean uncorrected visual acuity improved significantly post-exchange (logMAR 0.981 to 0.487, P < 0.001).
  • 78.7% of eyes achieved a refractive outcome within ±1.0 diopter.
  • Cystoid macular edema (CME) was the most frequent complication (7.6%).
  • Iris-sutured technique showed higher dislocation rates (10.3%), while Yamane technique had higher IOL tilt rates (11.8%).

Conclusions:

  • IOL exchange effectively improves visual acuity and refractive outcomes.
  • Surgical technique choice influences complication profiles, with specific risks for iris-sutured and Yamane techniques.
  • Findings aid surgeons in preoperative planning for IOL exchange procedures.