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The emergence of BtSY2 Covid-like virus: A call for global preparedness
Pius O Omosigho1, John O Okesanya2, Olaleke N Olabode3
1Department of Medical Laboratory Science, Edo State University Uzairue, Benin, Nigeria.
Abstract:
Scientists in China announced on 25th of November with great concern that there is a new Covid-like virus out of the five viruses of concern discovered among bats across Yunnan province. It was reported that this Covid-like virus BtSY2 has high potential of infecting humans as it comprises a receptor binding domain which is a vital part of the spike protein used to lay hold of human cells and subsequently utilize human ACE2 receptor for cell entry similar to the SARS-CoV-2. In a bid to address this global threat in affected countries, it is expedient for authorized health professionals, policy makers and the world to keep an eye on this Covid-like virus capable of spreading from bats to humans because most pandemic outbreaks in recent decades have arisen in such a manner. Strict actions should be implemented in impeding transmission to humans which is paramount to battling viral diseases as learnt from history that viral outbreaks are very impossible to eradicate after global outbreak. Health officials and the World Health Organization should invest urgently in more research to further study this new Covid-like virus with an approach to prepare for a possible viral outbreak, and develop treatment options and possible vaccines to outsmart the danger posed to human health.
Insights
A new bat virus, BtSY2, discovered in China shows potential for human infection, similar to SARS-CoV-2. Urgent research and surveillance are recommended to prevent a potential pandemic.
Area of Science:
- Virology
- Zoonotic Diseases
- Public Health
Background:
- Five viruses of concern were discovered among bats in Yunnan province, China.
- A novel Covid-like virus, designated BtSY2, was identified.
- This virus exhibits characteristics concerning for potential human spillover.
Purpose of the Study:
- To report the discovery of a new bat virus with pandemic potential.
- To highlight the structural similarities of BtSY2 to SARS-CoV-2, indicating potential human infectivity.
- To emphasize the need for global vigilance and preparedness against zoonotic threats.
Main Methods:
- Bat surveillance in Yunnan province, China.
- Genomic analysis to identify and characterize novel viruses.
- Comparative analysis of viral spike proteins and receptor binding domains.
Main Results:
- Discovery of the BtSY2 virus in bats.
- Identification of a receptor binding domain in BtSY2 similar to SARS-CoV-2.
- BtSY2 demonstrates potential for binding to human ACE2 receptors, facilitating cell entry.
Conclusions:
- The BtSY2 virus poses a potential threat for human infection and future outbreaks.
- Continuous monitoring of bat populations and emerging viruses is crucial for pandemic prevention.
- Urgent research, policy-making, and global health initiatives are necessary to prepare for and mitigate potential zoonotic viral threats.
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