Related Experiment Video
Updated: Aug 4, 2025
06:55
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
12.1K
Gallbladder Paraganglioma: A Mysterious Histological Finding
Jee Eun Do1,2, Kathryn Harvey3, Abdul Rana1
1Department of Surgery, The Queen Elizabeth Hospital, Adelaide, AUS.
Cureus
|March 30, 2023
Summary
Gallbladder paragangliomas are rare tumors. For asymptomatic, nonsecretory cases without endocrine syndrome history, cholecystectomy and follow-up may suffice.
Area of Science:
- Oncology
- Endocrinology
- Surgical Pathology
Background:
- Gallbladder paragangliomas are exceedingly rare neuroendocrine tumors, with limited reported cases.
- No established clinical guidelines exist for managing gallbladder paragangliomas due to their rarity.
Observation:
- A 53-year-old male underwent laparoscopic cholecystectomy for right upper quadrant pain.
- Post-operative pathological examination revealed an incidental gallbladder paraganglioma.
Findings:
- Literature review indicates all previously reported gallbladder paragangliomas were nonsecretory and benign.
- The presented case was also nonsecretory and benign.
Implications:
- Cholecystectomy followed by clinical surveillance may represent adequate initial management for incidentally discovered, asymptomatic, nonsecretory gallbladder paragangliomas.
- This approach is particularly relevant for patients without a family history of endocrine syndromes.
