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Does Premature Ventricular Complex Impair Left Ventricular Diastolic Functions?
Nursen Keleş1, Erkan Kahraman1, Kemal Emrecan Parsova2
1Department of Cardiology, University of Health Sciences, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Türkiye.
Anatolian Journal of Cardiology
|March 30, 2023
Summary
Patients with frequent premature ventricular complexes (PVCs) show impaired left ventricle diastolic function. Early diastolic strain rate, a key measure, is significantly lower in PVC patients, indicating a higher risk of diastolic dysfunction.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Physiology
Background:
- Frequent premature ventricular complexes (PVCs) are linked to cardiomyopathy.
- Left ventricular systolic function in PVC patients is studied, but diastolic function remains unclear.
- This study investigates PVCs' impact on left ventricular diastolic function.
Purpose of the Study:
- To assess left ventricular diastolic function in patients with frequent PVCs.
- To determine if early diastolic strain rate can predict diastolic dysfunction in PVC patients.
- To compare diastolic function between PVC patients and healthy controls.
Main Methods:
- Echocardiography and 2D speckle tracking analysis were used.
- Systolic and diastolic strain parameters were measured.
- Early diastolic strain rate was averaged across 17 cardiac segments.
Main Results:
- Patients with frequent PVCs had significantly lower early diastolic strain rate than controls (1.62 ± 0.58 vs. 1.25 ± 0.38, P <.001).
- Negative correlations were found between QRS duration/coupling interval and early diastolic strain rate.
- Positive associations existed between coupling interval and early diastolic strain rate.
Conclusions:
- Patients with PVCs exhibit reduced early diastolic strain rate.
- Early diastolic strain rate is a potential predictor of left ventricle diastolic dysfunction.
- PVC patients may face an elevated risk of developing left ventricle diastolic dysfunction.
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