Related Experiment Video
Updated: Aug 4, 2025

Zinc-finger Nuclease Enhanced Gene Targeting in Human Embryonic Stem Cells
Published on: August 23, 2014
Gene Targeting in Rat Embryonic Stem Cells
Hongsheng Men1, Daniel J Davis2, Elizabeth C Bryda3,2
1Rat Resource and Research Center, University of Missouri, Columbia, MO, USA. menho@missouri.edu.
Abstract:
Rat germline-competent embryonic stem (ES) cell lines have been available since 2008, and rat models with targeted mutations have been successfully generated using ES cell-based genome targeting technology. This chapter will focus on the procedures of gene targeting in rat ES cells.
More Related Videos
08:24CRISPR-Cas9 Genome Editing of Rat Embryos using Adeno-Associated Virus AAV and 2-Cell Embryo Electroporation
Published on: March 15, 2024
10:57CRISPR/Cas9-Mediated Highly Efficient Gene Targeting in Embryonic Stem Cells for Developing Gene-Manipulated Mouse Models
Published on: August 24, 2022