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Fluid compartments influence elastography of the aging mouse brain.

Gary R Ge1, Jannick P Rolland1, Wei Song2

  • 1Institute of Optics, University of Rochester, 480 Intercampus Drive, Box 270186, Rochester, NY 14627, United States of America.

Physics in Medicine and Biology
|March 30, 2023
PubMed
Summary

Brain stiffness increases significantly with age, correlating with reduced fluid content. Elastography may serve as a biomarker for age-related brain changes, including alterations in the glymphatic system.

Keywords:
agingbiphasic modelbrainfluid dynamicsoptical elastographyrheology

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