Pediatric vulvar lichen sclerosus: Does it resolve or does it persist after menarche?
Veronica Boero1, Riccardo Cavalli2, Carlotta Caia1,3
1Gynecology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pediatric Dermatology
|March 30, 2023
Summary
Pediatric vulvar lichen sclerosus (pVLS) often persists beyond puberty, with most patients continuing to show signs after menarche. Long-term follow-up is crucial, even if symptoms initially resolve.
Area of Science:
- Pediatric Dermatology
- Gynecology
- Dermatology
Background:
- Pediatric vulvar lichen sclerosus (pVLS) is increasingly recognized as a condition that can persist beyond puberty.
- Previous data on pVLS remission and progression rates are limited.
- Studies suggest up to 75% of pVLS cases may persist into adulthood.
Purpose of the Study:
- To investigate the evolution of pediatric vulvar lichen sclerosus (pVLS) after menarche.
- To determine the persistence and remission rates of pVLS in post-menarcheal patients.
Main Methods:
- Observational retrospective study.
- Involved 31 premenarchal girls diagnosed with pVLS between 1990 and 2011.
- Follow-up included multidisciplinary clinical evaluation after menarche.
Main Results:
- Mean follow-up duration was 14 years.
- 58% of patients remained affected by vulvar lichen sclerosus (VLS) post-menarche.
- 16% achieved complete remission, while 26% were asymptomatic with persistent clinical signs.
Conclusions:
- Pediatric vulvar lichen sclerosus (pVLS) persists in the majority of patients following menarche.
- Long-term monitoring is essential for all patients, including those reporting symptom resolution.
- Persistent clinical signs warrant continued follow-up despite asymptomatic presentation.
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