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Updated: Aug 4, 2025

Author Spotlight: Rapid Prototyping and Testing of Self-Expanding Nitinol Frames for Transcatheter Implantable Devices
Published on: March 7, 2025
The case of the missing spacer!
Andrea Boerkamp1,2, Marie Shella De Robles1,3,2
1Department of Surgery, Shoalhaven District Memorial Hospital, Nowra, New South Wales 2541, Australia.
The SpaceOAR Vue hydrogel system, used in prostate cancer radiation therapy, has shown rare complications including rectal erosion and fistula formation. Careful consideration of these risks is necessary as its use becomes more widespread.
Area of Science:
- Oncology
- Medical Devices
- Radiation Therapy
Background:
- The SpaceOAR Vue hydrogel system was designed to mitigate rectal toxicity during prostate cancer radiation therapy.
- Initial studies indicated favorable safety and efficacy profiles for the hydrogel system.
Observation:
- Increased utilization of the SpaceOAR Vue hydrogel system has been associated with emerging complications.
- A specific case involved rectal erosion, abscess, and fistula formation linked to the hydrogel.
Findings:
- The SpaceOAR Vue hydrogel was found to be absent during treatment, suggesting rectal passage through the fistula.
- This case highlights a rare but severe complication of the SpaceOAR Vue hydrogel system.
Implications:
- The study discusses the benefits and potential complications of the SpaceOAR Vue hydrogel system.
- Key factors for consideration are presented as the routine recommendation for this device increases.
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