Related Experiment Video

Updated: Aug 4, 2025

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
03:10

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid

Published on: November 1, 2024

2.7K

An Observational Study of Clinical, Metabolic and Hormonal Profile of Pediatric Acne

Vipul Pareek1, Niti Khunger1, Shobha Sharma2

  • 1Department of Dermatology and STD, VMMC and SJH, New Delhi, India.

Indian Journal of Dermatology
|March 31, 2023
PubMed

Insights

Pediatric acne, common in children aged 1-12, primarily presents as comedones and papules. While blood sugar and HDL levels show a weak correlation with acne severity, severe acne is rare in this age group.

Area of Science:

  • Pediatric Dermatology
  • Biochemistry
  • Endocrinology

Background:

  • Acne vulgaris is a common skin condition in children, with varying presentations and severity.
  • Understanding the biochemical, metabolic, and hormonal factors associated with pediatric acne is crucial for effective management.

Purpose of the Study:

  • To investigate the biochemical, metabolic, and hormonal profiles of children with acne.
  • To determine the correlation between these profiles and the grading of acne in pediatric patients.

Main Methods:

  • An observational, cross-sectional study was conducted over 18 months.
  • Fifty children aged 1-12 years with clinical acne features were assessed for acne type, biochemical profile (lipid profile, blood sugar), and hormonal profile.
  • Spearman's rank correlation was used to analyze the relationship between acne grading and metabolic/hormonal changes.

Main Results:

  • Comedones (98%) and papules (94%) were the most frequent acne lesions.
  • Children aged 8-12 years had significantly more comedones and fewer pustules compared to younger children (1-7 years).
  • A significant negative correlation was found between fasting blood sugar and acne grading (r = -0.312, P = 0.0275), and a significant positive correlation between HDL and acne grading (r = 0.28, P = 0.0491).

Conclusions:

  • Comedones and papules are the predominant early signs of pediatric acne.
  • Severe acne is uncommon in children under 12 years old, with preadolescent acne being more prevalent than mid-childhood acne.
  • Metabolic factors, including blood sugar levels and lipid profiles, exhibit a weak correlation with the severity of acne in children.
Abstract

Keywords:
Acnehormonalmetabolicpediatric

More Related Videos

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach09:32

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach

Published on: September 26, 2019

7.2K
Assessment of Child Anthropometry in a Large Epidemiologic Study09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

27.2K

Related Concept Videos

Observational Studies01:11

Observational Studies

Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.8K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
6.9K
Assessment of Airway, Skin Color, and Use of Accessory Muscles01:30

Assessment of Airway, Skin Color, and Use of Accessory Muscles

A thorough assessment of respiratory health is paramount in clinical settings to identify and manage respiratory distress and ensure adequate oxygenation. This article elaborates on the critical aspects of respiratory evaluation, including airway assessment, skin color examination, and the observation of accessory muscle use, which are integral to effectively diagnosing and managing patients with respiratory conditions.
Introduction
The initial evaluation of a patient's respiratory system...
1.1K
Data Collection by Observations01:08

Data Collection by Observations

Data collection refers to a systematic way of obtaining, observing, measuring, and analyzing accurate information. Observational studies are one of the most widely used methods of data collection. It involves collecting data by observing the behavior and physical characteristics of a sample without making any modifications to the sample.
An astronomer viewing the motion and brightness of stars in the sky and recording the data is an example of observational data collection. A botanist recording...
12.2K