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Cecilie Jansen1, Peter Vilmann1, Lene Brink1

  • 1Kikkertundersøgelse, Afdeling for Mave-, Tarm- og Leversygdomme, Herlev og Gentofte Hospital - Københavns Universitetshospital.

Ugeskrift for Laeger
|March 31, 2023
PubMed
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Radiofrequency ablation (RFA) successfully treated malignant biliary obstruction in Denmark. This innovative approach improved stent patency, enabling continued palliative therapy for a Klatskin tumour patient.

Area of Science:

  • Interventional Gastroenterology
  • Oncology
  • Hepatobiliary Surgery

Background:

  • Malignant biliary obstruction, often caused by Klatskin tumours, presents a significant challenge in palliative care.
  • Recurrent stent occlusion complicates management, hindering effective treatment delivery.
  • Neoadjuvant therapy is a common approach for managing such tumours.

Observation:

  • A 59-year-old male with a Klatskin tumour experienced recurrent bile duct stent occlusions during neoadjuvant therapy.
  • Endoluminal radiofrequency ablation (RFA) was proposed to reduce tumour burden and improve stent patency.
  • The RFA procedure was successfully performed without adverse events.

Findings:

  • The endoluminal RFA achieved access to previously occluded left hepatic ducts.

Related Experiment Videos

  • The procedure aimed to facilitate the resumption of palliative therapy.
  • This represents the first reported case of endoluminal RFA for a Klatskin tumour in Denmark.

    • Implications:

    • Endoluminal RFA offers a potential solution for managing malignant biliary obstruction with recurrent stent occlusions.
    • This technique may improve stent patency and enable the continuation of palliative treatments.
    • Further research is warranted to establish the efficacy and long-term outcomes of RFA in this context.