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Surgical management of dermatofibrosarcoma protuberans
Dylan J Rust1,2, Bradley D Kwinta1,3, Larisa J Geskin1,3
1Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Journal of Surgical Oncology
|March 31, 2023
Summary
Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. This review examines optimal surgical treatments, including Mohs surgery, for managing this locally aggressive malignancy.
Area of Science:
- Dermatology
- Surgical Oncology
- Cutaneous Malignancies
Background:
- Dermatofibrosarcoma protuberans (DFSP) is an uncommon skin cancer.
- It is known for being locally aggressive.
- Complete surgical resection is the main treatment approach.
Purpose of the Study:
- To review the current management strategies for DFSP.
- To focus on the optimal surgical approach for DFSP.
- To discuss the debate surrounding the best surgical method.
Main Methods:
- Literature review of current management guidelines and studies.
- Analysis of traditional versus modern surgical techniques.
- Discussion of medical therapy options for advanced cases.
Main Results:
- Wide local excision was the historical standard for DFSP treatment.
- Current National Comprehensive Cancer Network guidelines favor Mohs micrographic surgery.
- Imatinib is an option for unresectable or advanced DFSP.
Conclusions:
- The optimal surgical approach for DFSP is a key consideration.
- Mohs micrographic surgery is increasingly recommended.
- Management decisions should be individualized based on disease extent and patient factors.
