Coronary Artery Aneurysms as a Cause of Acute Coronary Syndrome Presentation - A Focused Review
Azka Latif1, Amy Tran2, Junaid Ahsan3
1Division of Cardiovascular Medicine, Baylor College of Medicine, Houston, Texas, USA.
Insights
Coronary artery aneurysms (CAA) can cause acute coronary syndrome (ACS) symptoms like chest pain. Current management strategies for CAA are unclear due to varied presentations and unknown causes.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Coronary artery aneurysms (CAA) are dilations exceeding 1.5 times local diameter.
- CAAs often present incidentally but can lead to severe complications including thrombosis, embolization, ischemia, arrhythmias, and heart failure.
Approach:
- This review discusses the role of CAAs in acute coronary syndrome (ACS) presentations.
- It examines current management strategies for coronary artery aneurysms.
Key Points:
- Chest pain is the most common symptom in symptomatic CAA cases.
- CAA pathophysiology is not fully understood, complicating diagnosis and management.
- Variable presentations mimic other acute coronary syndromes, hindering clear treatment pathways.
Conclusions:
- Understanding CAA's contribution to ACS is crucial.
- Further research is needed to establish clear management guidelines for coronary artery aneurysms.
Abstract:
Coronary artery aneurysms (CAA) are defined as a dilation of a coronary vessel greater than 1.5 times the diameter of a local reference vessel. While CAAs tend to be incidental findings on imaging, they result in complications, such as thrombosis, embolization, ischemia, arrhythmias, and heart failure. Among symptomatic cases, chest pain has been the most common manifestation of CAAs. This necessitates an understanding of CAAs as a cause of acute coronary syndrome (ACS) presentation. However, due to the unclear pathophysiology of CAAs and their variable presentation complicated by similar ACS conditions, there is no clear strategy for CAA management. In this article, we will discuss the contribution of CAAs to ACS presentations and review the current management options for CAAs.
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