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Detecting dengue fever in children using online Rasch analysis to develop algorithms for parents: An APP development
Ting-Yun Hu1, Julie Chi Chow1,2, Tsair-Wei Chien3
1Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan.
Medicine
|March 31, 2023
Summary
This study developed a logistic regression app to aid parents in detecting dengue fever in children. The app helps differentiate dengue from other febrile illnesses early on.
Area of Science:
- Medical Informatics
- Machine Learning in Healthcare
- Public Health Surveillance
Background:
- Dengue fever (DF) poses a significant public health challenge in Asia.
- Traditional DF detection methods are often difficult.
- Machine learning models like CNNs and ANNs show promise for improving prediction accuracy.
Purpose of the Study:
- To investigate the effectiveness of combining CNN, ANN, KNN, and LR for DF prediction in children.
- To explore item features and responses using online Rasch analysis for DF detection.
- To develop a practical tool for early DF diagnosis in pediatric patients.
Main Methods:
- Extracted 19 DF symptom variables from 177 pediatric patients (69 with DF).
- Utilized Rasch analysis to examine 11 variables for DF risk prediction.
- Calculated prediction accuracy (AUC) using training (80%) and testing (20%) datasets, comparing combined algorithms vs. individual ones.
Main Results:
- Rasch analysis provided easily interpretable visual displays of DF data.
- Logistic Regression (LR) achieved a relatively high AUC (0.70).
- An app was developed to assist parents in detecting DF in children.
Conclusions:
- An LR-based mobile application for pediatric DF detection has been successfully developed.
- An 11-item model is proposed to aid early differentiation of DF from other febrile illnesses.
- The app aims to support patients, families, and clinicians in timely DF diagnosis.

