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Associations between low birth weight and perinatal asphyxia: A hospital-based study
Zhao-Na Li1, Shu-Rong Wang, Ping Wang
1Neonatal Department, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.
Medicine
|March 31, 2023
Summary
Low birth weight (LBW) is a significant risk factor for perinatal asphyxia, a serious condition affecting newborns. This study highlights LBW as a key contributor to birth asphyxia, emphasizing the need for targeted interventions.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Medicine
- Perinatal Health
Background:
- Perinatal asphyxia poses a significant threat to newborn health.
- Identifying risk factors for perinatal asphyxia is crucial for effective prevention and management.
- Low birth weight (LBW) is a suspected contributor to adverse perinatal outcomes.
Purpose of the Study:
- To investigate the association between low birth weight (LBW) and perinatal asphyxia.
- To identify maternal and newborn factors contributing to perinatal asphyxia.
Main Methods:
- Hospital-based study involving 150 mothers and their newborns from 2018.
- Participants categorized into case (perinatal asphyxia) and control groups.
- Bivariable and multivariable logistic regression analyses employed to assess risk factors.
Main Results:
- Bivariate analysis indicated significant associations between LBW, maternal age < 20 years, and gestational age with perinatal asphyxia.
- Multivariate analysis revealed LBW, male newborns, preeclampsia/eclampsia, primiparity, and gestational age > 37 weeks as risk factors for perinatal asphyxia.
- No significant association found between maternal age or antenatal care history and perinatal asphyxia.
Conclusions:
- Low birth weight (LBW) is a significant risk factor for developing perinatal asphyxia.
- Specific maternal and newborn characteristics increase the risk of perinatal asphyxia.
- Further research may inform targeted interventions to reduce the incidence of perinatal asphyxia in at-risk infants.
