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Updated: Aug 4, 2025

Real-Time Void Spot Assay
Published on: February 10, 2023
Nocturnal polyuria and nocturia
Shachi Tyagi1, Michael B Chancellor2
1Department: Medicine, Division: Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, USA.
Background:
Nocturia is a common complaint that can have a significant impact on quality of life. The pathophysiology is usually multifactorial and can be due to poor sleep, nocturnal polyuria, or low bladder capacity alone or in combination.
Objective:
Nocturnal polyuria (NP) is the most common cause of nocturia in older adults. We hereby review the role of nocturnal polyuria in nocturia.
Patients And Methods:
To manage nocturia, a multipronged approach personalized to the patient's multifactorial etiology is warranted, with a focus on lifestyle modifications and behavioral approaches as first-line therapies. Pharmacologic treatment should be considered based on underlying disease processes, and healthcare providers should be mindful of potential drug interactions and polypharmacy in older adults.
Result:
Referral to specialists in sleep or bladder-related disorders may be necessary for some patients. With comprehensive and individualized management, patients with nocturia can achieve improved quality of life and overall health outcomes.
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