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Essential element nutritional status in cystic fibrosis
Human Nutrition. Applied Nutrition
|April 1, 1986
Summary
Patients with cystic fibrosis (CF) often have low serum iron, suggesting a need for iron supplementation. Other essential mineral levels, including calcium, magnesium, copper, and zinc, were generally well-maintained in CF patients.
Area of Science:
- Clinical Biochemistry
- Pediatric Medicine
- Nutritional Science
Background:
- Cystic Fibrosis (CF) is a genetic disorder affecting multiple organs.
- Nutritional deficiencies are common in CF due to malabsorption.
- Essential mineral status in CF patients requires ongoing investigation.
Purpose of the Study:
- To assess serum levels of essential minerals in cystic fibrosis patients.
- To determine if supplementation is needed for specific minerals in CF.
- To investigate correlations between clinical parameters and mineral status.
Main Methods:
- Serum levels of calcium, magnesium, iron, copper, and zinc were measured.
- 117 patients with cystic fibrosis participated in the study.
- Clinical data including age, fat malabsorption, clinical grading, and pulmonary involvement were considered.
Main Results:
- Serum iron levels were frequently low in CF patients.
- Serum levels of calcium, magnesium, copper, and zinc were generally adequate.
- No significant correlation was found between clinical parameters and serum mineral levels.
Conclusions:
- Low serum iron is a common finding in cystic fibrosis patients.
- Routine supplementation of calcium, magnesium, copper, and zinc is likely unnecessary in CF.
- Further research is warranted to confirm the need for iron supplementation in CF.