Related Experiment Video
Updated: Aug 4, 2025

08:50
Predictive Immune Modeling of Solid Tumors
Published on: February 25, 2020
7.0K
Correction: Tumor immunogenomic signatures improve a prognostic model of melanoma survival
Leah Morales1,2,3, Danny Simpson1,2,3, Robert Ferguson1,2,3
1Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, 522 First Avenue, New York City, NY, 10016, USA.
Journal of Translational Medicine
|April 2, 2023
Abstract
No abstract available in PubMed .
Related Concept Videos
Tumor Immunotherapy
598
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
598
Tumor Progression
6.4K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.4K

