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Particle carriers for controlled release of peptides
Emily Y Jiang1, Shelby T Desroches1, Antonios G Mikos1
1Department of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, USA.
Summary
Researchers are developing advanced carriers for therapeutic peptides, focusing on nanoparticles and microparticles. These systems utilize specific interactions to overcome challenges in controlled peptide release for drug delivery and tissue engineering applications.
Area of Science:
- Biomaterials Science
- Drug Delivery Systems
- Nanotechnology
Background:
- Therapeutic peptides are increasingly used in drug delivery and tissue engineering.
- Peptides offer advantages over proteins due to better bioactivity retention in formulations.
- Controlled release of small peptides from carriers remains a significant challenge.
Conclusions:
- Carrier design is crucial for overcoming challenges in therapeutic peptide delivery.
- Understanding peptide-carrier interactions enables the development of effective controlled-release systems.
- Further research into novel nanoparticles and microparticles will advance peptide-based therapies.
