Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

243
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
243
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

380
The pathophysiology of pneumonia involves the following steps:
380
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

298
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
298
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

15
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
15
Pneumothorax-I01:26

Pneumothorax-I

274
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
274
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

2.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of severe acute alcoholic hepatitis in France: results of a national survey: R1.

Clinics and research in hepatology and gastroenterology·2026
Same author

Effects of Scutellaria baicalensis extract on inflammatory biomarkers and performance in transition dairy cows.

Journal of dairy science·2026
Same author

Beyond the shunt: Divergent insights from hyperoxia testing and contrast echocardiography in adults with pulmonary hypertension.

Physiological reports·2025
Same author

Comparison between a complete preconditioning programme and conventional conduct on behaviour, health and performance of young bulls from small cow-calf herds.

Animal : an international journal of animal bioscience·2024
Same author

Pulmonary hypertension in connective tissue diseases: What every CTD specialist should know - but is afraid to ask!

La Revue de medecine interne·2023
Same author

[Dysfunction of endothelial BMP-9 signaling in pulmonary vascular disease].

Revue des maladies respiratoires·2023
Same journal

[Atypical low back pain].

La Revue de medecine interne·2026
Same journal

[Polycythemia associated chronic haemolysis].

La Revue de medecine interne·2026
Same journal

[Persistent headaches in a 55 year-old man].

La Revue de medecine interne·2026
Same journal

[Abdominal pain, fever and arthralgia in a 49-year-old woman].

La Revue de medecine interne·2026
Same journal

[Cardiorespiratory functional disorders: A transnosologic approach].

La Revue de medecine interne·2026
Same journal

[Diagnostic evaluation for suspected polycythemia].

La Revue de medecine interne·2026
See all related articles

Related Experiment Video

Updated: Aug 4, 2025

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
09:37

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Published on: August 1, 2018

15.1K

[Hepatopulmonary syndrome].

A Sayadi1, L Duhaut1, F Robert2

  • 1UMR-S 1193, hôpital Paul-Brousse, centre hépato-biliaire, université Paris-Saclay, AP-HP, 94800 Villejuif, France.

La Revue De Medecine Interne
|April 2, 2023
PubMed
Summary
This summary is machine-generated.

Hepatopulmonary syndrome (HPS), a lung complication of cirrhosis, involves dilated pulmonary vessels impacting gas exchange. Liver transplantation offers a cure, significantly improving survival rates for affected patients.

Keywords:
CirrhoseCirrhosisHepatopulmonary syndromeHypertension portaleLiver transplantationPortal hypertensionSyndrome hépato-pulmonaireTransplantation hépatique

More Related Videos

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
07:29

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

10.9K
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

50.1K

Related Experiment Videos

Last Updated: Aug 4, 2025

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
09:37

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Published on: August 1, 2018

15.1K
The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats
07:29

The Left Pneumonectomy Combined with Monocrotaline or Sugen as a Model of Pulmonary Hypertension in Rats

Published on: March 8, 2019

10.9K
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

50.1K

Area of Science:

  • Cardiology
  • Pulmonology
  • Hepatology

Context:

  • Hepatopulmonary syndrome (HPS) is a serious complication in patients with cirrhosis and portal hypertension.
  • HPS presents as dyspnea and is characterized by intrapulmonary vascular dilatations (IPVD).

Purpose:

  • To define hepatopulmonary syndrome (HPS), its diagnostic criteria, and its impact on patient prognosis.
  • To review the efficacy of liver transplantation (LT) as the primary curative treatment for severe HPS.

Summary:

  • HPS diagnosis requires liver disease, portal hypertension, IPVD, and impaired gas exchange (A-aO2 ≥ 15mmHg).
  • Severe HPS (PaO2 < 60mmHg) necessitates liver transplantation for improved survival (76-87% at 5 years).
  • Palliative oxygen therapy is an option when LT is not feasible, but further research into pathophysiological mechanisms is needed.

Impact:

  • HPS significantly impairs quality of life and prognosis, with a 5-year survival rate of only 23% without treatment.
  • Liver transplantation effectively reverses IPVD, normalizes gas exchange, and dramatically improves long-term survival.
  • Understanding HPS pathophysiology could lead to novel therapeutic strategies beyond current treatment options.