Gastrointestinal symptoms in COVID-19
Konrad Lewandowski1, Magdalena Kaniewska1, Mariusz Rosołowski2,3
1Department of Internal Medicine and Gastroenterology with Inflammatory Bowel Disease Unit, Central Clinical Hospital of Ministry of Inferior and Administration, Warsaw, Poland.
Przeglad Gastroenterologiczny
|April 3, 2023
Summary
COVID-19 affects the respiratory and digestive systems. This review examines meta-analyses on gastrointestinal symptoms and gut microbiome disturbances in SARS-CoV-2 infection.
Area of Science:
- Gastroenterology
- Virology
- Microbiology
Background:
- SARS-CoV-2 primarily impacts the respiratory system.
- Gastrointestinal symptoms are common in COVID-19, indicating digestive system involvement.
- The pathogenesis of these abdominal symptoms is multifaceted.
Purpose of the Study:
- To provide an overview of key meta-analyses and publications.
- To explore the relationship between COVID-19, gastrointestinal symptoms, and the gut microbiome.
- To summarize current understanding of the gut's role in SARS-CoV-2.
Main Methods:
- Literature review of meta-analyses and publications.
- Synthesis of data on gastrointestinal manifestations of COVID-19.
- Analysis of studies investigating gut microbiome alterations.
Main Results:
- The digestive system is significantly involved in COVID-19 expression and pathogenesis.
- Potential mechanisms include angiotensin 2 receptor interactions and cytokine storms.
- Disturbances in the gut microbiome are frequently observed in COVID-19 patients.
Conclusions:
- COVID-19 has a notable impact on the gastrointestinal tract.
- Understanding gut microbiome changes is crucial for managing COVID-19.
- Further research is needed on the gut's role in SARS-CoV-2 transmission and pathogenesis.
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