Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alpha- and gamma tocopherol concentrations in human serum.

W A Behrens, R Madère

    Journal of the American College of Nutrition
    |January 1, 1986
    PubMed
    Summary

    Serum vitamin E levels, including alpha- and gamma-tocopherol, were analyzed in healthy adults. Alpha-tocopherol increased with age and lipids, while gamma-tocopherol did not, suggesting an interrelationship between these vitamin forms.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Influence of sources of dietary vitamin E on the maternal transfer of alpha-tocopherol to fetal and neonatal guinea pigs as determined by a stable isotopic technique.

    The British journal of nutrition·2003
    Same author

    Gender and exercise influence on tissue antioxidant vitamin status in rats.

    Journal of nutritional science and vitaminology·2000
    Same author

    Effect of chronic ethanol dosing on hepatic triglyceride and phospholipid profile and fatty acids in the guinea pig.

    Alcohol (Fayetteville, N.Y.)·1999
    Same author

    Estrogen administration, postexercise tissue oxidative stress and vitamin C status in male rats.

    Canadian journal of physiology and pharmacology·1999
    Same author

    Muscle vitamin E levels following acute submaximal exercise in female rats.

    Acta physiologica Scandinavica·1993
    Same author

    Effects of dietary linseed oil and marine oil on lipid peroxidation in monkey liver in vivo and in vitro.

    Lipids·1992

    Area of Science:

    • Nutritional Biochemistry
    • Human Physiology
    • Lipid Metabolism

    Background:

    • Vitamin E, comprising tocopherols and tocotrienols, is a crucial lipid-soluble antioxidant.
    • Alpha-tocopherol and gamma-tocopherol are the primary forms found in human serum.
    • Understanding their concentrations and interrelationships is vital for assessing nutritional status and health.

    Purpose of the Study:

    • To quantify serum concentrations of alpha-tocopherol and gamma-tocopherol in a healthy adult population.
    • To investigate the influence of age and total serum lipids on these vitamin E forms.
    • To explore the potential interrelationship and competition between alpha- and gamma-tocopherol.

    Main Methods:

    • Serum samples were collected from 451 healthy male and female subjects aged 19-70 years.
    • Concentrations of alpha-tocopherol and gamma-tocopherol were measured.
    • Total lipid levels in the serum were also determined.

    Main Results:

    • Mean serum alpha-tocopherol was 8.82 ± 2.84 µg/ml; mean gamma-tocopherol was 1.35 ± 0.70 µg/ml.
    • Alpha-tocopherol concentration significantly increased with age and total lipid levels.
    • Gamma-tocopherol concentration showed no significant change with age, but inverse relationships with alpha-tocopherol were observed.

    Conclusions:

    • Serum alpha-tocopherol levels are positively associated with age and lipid concentration in healthy adults.
    • A competitive or inverse relationship exists between serum alpha- and gamma-tocopherol concentrations.
    • These findings highlight the dynamic interplay of vitamin E forms in human physiology.

    Related Experiment Videos