Related Experiment Video
Updated: Aug 4, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Ocular Toxocariasis Presenting as Endophthalmitis in a Young Adult Intravenous Drug User
Pali P Singh1, Cason B Robbins1, Henry L Feng2
1Duke University School of Medicine, Durham, NC, USA.
Purpose:
This report describes the diagnosis of ocular toxocariasis presenting as endophthalmitis in an adult intravenous drug user.
Methods:
A case is reported.
Results:
Fundus imaging showed numerous white opacities obscuring the macula. Toxocara canis serology was reactive with an enzyme immunoassay titer of 1:2 (positive ≥ 1:32). Findings from bacterial and fungal cultures were negative, and vitrectomy cytology revealed no organisms. Postoperatively, serial optical coherence tomography imaging demonstrated a slight decrease in size of an intraretinal hyperreflective lesion in the macula.
Conclusions:
Owing to a variety of presentations, ocular toxocariasis can be challenging to diagnose. In a patient with a history of intravenous drug use where fungal and bacterial organisms are more common causes of endophthalmitis, it is important to have a wide differential of causative organisms, particularly in the context of negative culture results and a worsening clinical examination.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment

