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Bilateral Macular Holes in Adult Vitelliform Macular Dystrophy
Kathleen A Regan1, Justin L Gottlieb1
1Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI, USA.
Journal of Vitreoretinal Diseases
|April 3, 2023
Summary
This case report details bilateral macular holes in adult vitelliform macular dystrophy. Surgical repair was successful, leading to vision improvement despite retinal atrophy.
Area of Science:
- Ophthalmology
- Retinal Diseases
Background:
- Adult vitelliform macular dystrophy (AVMD) is a rare inherited macular disorder.
- Macular holes (MHs) are breaks in the macula, potentially causing vision loss.
Observation:
- A patient with AVMD developed sequential bilateral macular holes.
- Vitreomacular traction was identified as a potential precursor to MHs in both eyes.
Findings:
- Pars plana vitrectomy (PPV) with C3F8 gas tamponade successfully closed the macular holes in both eyes.
- Internal limiting membrane peeling was performed in the right eye, which required two PPVs for closure.
- Long-term retinal and retinal pigment epithelium atrophy were observed postoperatively in both eyes.
Implications:
- Vitreomacular traction may play a role in the pathogenesis of MHs in AVMD.
- Surgical intervention for MHs in AVMD can be effective in improving vision.
- Postoperative atrophy highlights the importance of long-term monitoring in these patients.

