Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Peptide-reinforced, photocrosslinkable PEG-based hydrogels.

RSC applied polymers·2026
Same author

Glucose Oxidase Initiates Radical Polymerizations by Direct Electron Transfer to Monomers.

Biomacromolecules·2025
Same author

Advanced mechanical properties of amphiphilic polymer conetworks through hierarchical reinforcement with peptides and cellulose nanocrystals.

Polymer chemistry·2025
Same author

Bacteria-Mediated Intracellular Radical Polymerizations.

Journal of the American Chemical Society·2025
Same author

Characterization and Optimization of Vesicle Properties in bioPISA: from Size Distribution to Post-Assembly Loading.

Advanced biology·2024
Same author

Large-area, self-healing block copolymer membranes for energy conversion.

Nature·2024

Related Experiment Video

Updated: Aug 4, 2025

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons
11:40

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

8.6K

Donor-acceptor Stenhouse adduct functionalised polymer microspheres.

Justus P Wesseler1, Grant M Cameron1, Peter A G Cormack1

  • 1WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde Thomas Graham Building 295 Cathedral Street Glasgow G1 1XL Scotland UK peter.cormack@strath.ac.uk.

Polymer Chemistry
|April 3, 2023
PubMed
Summary
This summary is machine-generated.

Light-responsive polymer microspheres functionalized with donor-acceptor Stenhouse adducts (DASAs) exhibit reversible property changes upon visible light irradiation. This innovation enables new applications in separation science and catalysis.

More Related Videos

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology
05:21

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology

Published on: May 16, 2022

3.0K
Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification
08:51

Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification

Published on: November 19, 2018

9.7K

Related Experiment Videos

Last Updated: Aug 4, 2025

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons
11:40

A Droplet-Based Microfluidic Approach and Microsphere-PCR Amplification for Single-Stranded DNA Amplicons

Published on: November 14, 2018

8.6K
Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology
05:21

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology

Published on: May 16, 2022

3.0K
Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification
08:51

Preparation of Polypentafluorophenyl acrylate Functionalized SiO2 Beads for Protein Purification

Published on: November 19, 2018

9.7K

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Photochemistry

Background:

  • Donor-acceptor Stenhouse adducts (DASAs) are light-responsive molecules enabling reversible property changes in materials.
  • Current DASA applications often involve dopants or pendent groups on linear polymers.
  • Covalent incorporation of DASAs into crosslinked polymer networks remains underexplored.

Purpose of the Study:

  • To synthesize and characterize DASA-functionalized crosslinked polymer microspheres.
  • To investigate the light-induced property changes of these novel DASA-polymer materials.
  • To explore potential applications in areas like microflow assays and separation science.

Main Methods:

  • Precipitation polymerization to create poly(divinylbenzene-co-4-vinylbenzyl chloride-co-styrene) microspheres.
  • Post-polymerization chemical modification to introduce trifluoromethyl-pyrazolone DASAs.
  • Solid-state Nuclear Magnetic Resonance (ssNMR) for DASA content verification and UV-Vis spectroscopy for switching dynamics.

Main Results:

  • Successful synthesis of DASA-functionalized polymer microspheres with varying DASA content.
  • Demonstrated reversible photoisomerization of incorporated DASAs upon visible light irradiation.
  • Observed significant changes in microsphere properties, including enhanced swelling, improved water dispersibility, and increased particle size.

Conclusions:

  • DASA-functionalized crosslinked polymer microspheres represent a promising new class of light-responsive materials.
  • These materials offer expanded application potential in polymer-supported reactions, separation science, and microfluidics.
  • This work lays the foundation for developing advanced light-responsive polymer supports for solid-phase extraction and catalysis.