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APOE-mediated suppression of the lncRNA MEG3 protects human cardiovascular cells from chronic inflammation

Hongkai Zhao1,2, Kuan Yang3,4,5, Yiyuan Zhang2,6,7

  • 1Division of Life Sciences and Medicine, School of Life Sciences, University of Science and Technology of China, Hefei 230001, China.

Protein & Cell
|April 3, 2023
PubMed
Abstract

No abstract available in PubMed .

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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