Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Menopause01:28

Menopause

217
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
217
Management of Insomnia01:19

Management of Insomnia

292
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
292
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

540
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
540
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

189
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
189
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

204
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
204
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

211
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
211

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prospective Associations Between Media Parenting Practices and Early Adolescent Screen Use: Findings From the Adolescent Brain Cognitive Development Study.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

Identifying menstrual metrics as personal health markers: Age trends and individual footprints in temperature across 5674 cycles.

Science advances·2026
Same author

Feasibility and acceptability of a sleep health intervention among adolescents in Ugandan schools: A prospective pilot intervention study.

Sleep advances : a journal of the Sleep Research Society·2026
Same author

Associations of Screen Time and Physical Activity With Body Mass Index in Early Adolescence: A Prospective Cohort Study.

Obesity (Silver Spring, Md.)·2026
Same author

Neural Sensitivity to Social Media Use: Implications for Sleep Duration in Adolescents.

Journal of sleep research·2026
Same author

Eating disorder symptoms are prospectively associated with higher BMI percentile in male early adolescents.

Eating and weight disorders : EWD·2026
Same journal

The International Menopause Society celebrates another milestone.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Impact of social determinants of health on perimenopause symptom burden: insights from the Flo app.

Climacteric : the journal of the International Menopause Society·2026
Same journal

From tissue to outcome - how perioperative vaginal estrogen transforms prolapse surgery results: a systematic review and meta-analysis of clinical evidence and outcomes.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Mapping menopause education for healthcare professionals: a scoping review.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Portuguese osteopaths' perceptions on the management of musculoskeletal conditions in menopausal women.

Climacteric : the journal of the International Menopause Society·2026
Same journal

Perimenopausal migraine: a narrative review.

Climacteric : the journal of the International Menopause Society·2026
See all related articles

Related Experiment Video

Updated: Aug 4, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.5K

Optimizing sleep across the menopausal transition.

F C Baker1,2

  • 1Center for Health Sciences and Human Sleep Research Program, SRI International, Menlo Park, CA, USA.

Climacteric : the Journal of the International Menopause Society
|April 3, 2023
PubMed
Summary
This summary is machine-generated.

Menopausal sleep disturbances, including night awakenings, are common. Both hormonal changes and vasomotor symptoms significantly impact sleep quality, affecting women

Keywords:
Menopauseclimactericdepressive symptomshot flashespolysomnographysleep architecturesubjective sleep qualityvasomotor symptoms

More Related Videos

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

15.5K
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K

Related Experiment Videos

Last Updated: Aug 4, 2025

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System
05:59

Author Spotlight: Overcoming Challenges in Drosophila Sleep Measurement Using DAM System

Published on: October 20, 2023

2.5K
A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
14:26

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

15.5K
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.4K

Area of Science:

  • Reproductive Endocrinology
  • Sleep Medicine
  • Women's Health

Background:

  • Sleep disturbances are prevalent in menopausal women, impacting daily functioning and health.
  • Vasomotor symptoms and hormonal shifts are key factors contributing to menopausal sleep issues.
  • These sleep problems can increase the risk of mental and physical health conditions.

Purpose of the Study:

  • To investigate the relationship between menopausal transition, hormonal changes, vasomotor symptoms, and sleep disturbances.
  • To explore the direct impact of the hormonal environment on sleep quality during menopause.
  • To review current management strategies for menopausal sleep disturbances.

Main Methods:

  • Review of literature on menopause, sleep disturbances, vasomotor symptoms, and hormonal changes.
  • Analysis of studies examining the association between estradiol, follicle-stimulating hormone, and sleep patterns.
  • Evaluation of the efficacy of cognitive behavioral therapy for insomnia and hormone therapy.

Main Results:

  • Vasomotor symptoms significantly correlate with increased night awakenings and time spent awake.
  • Lower estradiol and higher follicle-stimulating hormone levels are independently associated with sleep disturbances, even after controlling for other factors.
  • Cognitive behavioral therapy for insomnia and hormone therapy are effective treatments for menopausal sleep issues.

Conclusions:

  • Menopause-related sleep disturbances are multifactorial, involving both vasomotor symptoms and direct hormonal effects.
  • Understanding these mechanisms is crucial for developing targeted interventions.
  • Further research is needed to advance preventative and treatment strategies for midlife women's sleep health.