Related Experiment Video
Updated: Aug 4, 2025

Production of Modified Autologous Conditioned Serum and Ex Vivo Assessment of Its Healing Potential in Murine Corneal Epithelium
Published on: March 24, 2023
[AUTOLOGOUS SERUM AS A TREATMENT FOR THE OCULAR SURFACE DISEASE]
1Department of Ophthalmology, Barzilai Medical Center, Israel.
Introduction:
The autologous serum drops treatment is an advanced, effective and safe treatment for severe dry eye and recurrent epithelial erosions. It contains growth factors, proteins, and vitamins, similar to the tear layer. In a recent review by the American Academy of Ophthalmology, many studies included showed a significant effect of serum drops in treating dry eye and recurrent epithelial erosions. Notwithstanding the above, to date, no randomized controlled clinical trials have investigated the effectiveness of autologous serum drops. Moreover, serum drops concoction has strict regulations, and in Israel, it is available in a small handful of hospitals, which causes limited accessibility to this valuable treatment. Precautions must be taken when using serum drops to avoid bottle contamination and infections during storage.

