Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Recombination00:57

Viral Recombination

23.6K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.6K
Retrovirus Life Cycles01:10

Retrovirus Life Cycles

46.4K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.4K
Viral Mutations00:36

Viral Mutations

32.7K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.7K
Introduction to Virus01:28

Introduction to Virus

111
Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
111
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

62
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
62
Retroviruses02:33

Retroviruses

12.6K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Human polyomaviruses recently identified in humans].

Virologie (Montrouge, France)·2022
Same author

[Human bocavirus (HBoV): from discovery through molecular screening to observation by electron microscopy].

Virologie (Montrouge, France)·2022
Same author

Divergent differentiation of Merkel cell carcinoma between primary and metastatic lesions.

Annales de dermatologie et de venereologie·2021
Same author

Detection of SARS-CoV-2 antibodies using commercial assays and seroconversion patterns in hospitalized patients.

The Journal of infection·2020
Same author

Characteristics of human metapneumovirus infection in adults hospitalized for community-acquired influenza-like illness in France, 2012-2018: a retrospective observational study.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2020
Same author

Epidemiological survey in a day care center following toddler sudden death due to human metapneumovirus infection.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2019

Related Experiment Video

Updated: Aug 4, 2025

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
12:20

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses

Published on: December 29, 2015

21.5K

[Bocavirus: a new human parvovirus].

V Foulongne1, M Segondy1

  • 1aLaboratoire de virologie, Pôle d'infectiologie, hôpital Saint-Eloi, Centre hospitalier universitaire, 34295 Montpellier Cedex 5.

Virologie (Montrouge, France)
|April 4, 2023
PubMed
Summary

A novel human bocavirus (HBoV) has been identified in children with respiratory illness. Further research is needed to confirm its role in human disease due to frequent co-infections.

Area of Science:

  • Virology
  • Molecular Biology
  • Pediatrics

Context:

  • A novel virus, human bocavirus (HBoV), was discovered in respiratory samples from children.
  • HBoV belongs to the Bocavirus genus within the Parvoviridae family, genetically related to bovine and canine parvoviruses.
  • Recent studies indicate HBoV prevalence of 3-18% in children with respiratory disease globally.

Purpose:

  • To report the discovery and initial characterization of human bocavirus (HBoV).
  • To investigate the genetic variability and clinical presentation associated with HBoV infections.
  • To highlight the need for further studies to ascertain the pathogenic potential of HBoV.

Summary:

  • HBoV was identified using molecular techniques in young children presenting with respiratory disease.
Keywords:
BocavirusHBoVParvoviridaerespiratory tract infection

More Related Videos

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
10:03

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

Published on: August 1, 2013

17.0K
Cost-effective Method for Microbial Source Tracking Using Specific Human and Animal Viruses
11:29

Cost-effective Method for Microbial Source Tracking Using Specific Human and Animal Viruses

Published on: December 3, 2011

12.2K

Related Experiment Videos

Last Updated: Aug 4, 2025

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
12:20

Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses

Published on: December 29, 2015

21.5K
Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
10:03

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells

Published on: August 1, 2013

17.0K
Cost-effective Method for Microbial Source Tracking Using Specific Human and Animal Viruses
11:29

Cost-effective Method for Microbial Source Tracking Using Specific Human and Animal Viruses

Published on: December 3, 2011

12.2K
  • Genetic analysis reveals low variability in HBoV strains.
  • Clinical signs associated with HBoV are similar to other respiratory viruses, and co-infections with other pathogens are common, obscuring HBoV's exact role.

    • Impact:

    • The discovery of HBoV expands our understanding of viral respiratory pathogens in children.
    • Low genetic variability suggests potential for targeted diagnostics or therapeutics.
    • Clarifying HBoV's pathogenic role is crucial for accurate diagnosis and management of pediatric respiratory infections.