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CRM and partial order CRM with adaptive rescaling for dose-finding in immunotherapy trials with a continuous outcome

Pooja T Saha1, Jason P Fine1, Anastasia Ivanova1

  • 1Department of Biostatistics, CB #7420, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Statistics in Medicine
|April 4, 2023
PubMed

Keywords:
continual reassessment methodpartial orderphase 1 clinical trialsquasi-likelihood

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