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Published on: October 13, 2023
IgG4-RD in a Unilateral Parotid Mass: A Rare Manifestation and Review of the Literature
Mayuri A Yasuda1, Morgan Sandelski2, Richard Borrowdale2
1Otolaryngology, Loyola University Chicago Stritch School of Medicine, Maywood, USA.
Abstract:
IgG4 related disease (IgG4-RD) is a rare, immune-mediated inflammatory disease that varies widely in its presentation because it can affect nearly any organ. We present a case of a 73-year-old male who presented with an ill-defined mass of the parotid gland, found to be IgG4-RD, after several months of work up and tissue sampling. Most cases of salivary gland involvement in IgG4-RD present as bilateral swelling of the submandibular glands. We present this case as a unique manifestation of salivary gland disease in IgG4-RD as a persistent, non-discrete unilateral mass in the parotid gland. It is critical that clinicians who regularly treat salivary gland pathologies are familiar with this rare disease and its potential manifestations in the oral cavity.
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