Related Experiment Video
Updated: Jun 25, 2026
06:55
Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
20.5K
The Pathogen Isolates in Chronic Wound Infections in Poland
Marcin Malka1, Arkadiusz Krakowiecki1, Magdalena Chojak1
11PODOS Wound Care Clinic, Warsaw, Poland.
Polish Journal of Microbiology
|April 4, 2023
Summary
Chronic wound infections, particularly in diabetic foot syndrome, are common. This study analyzed 3,917 microbiological tests from 1,199 patients, identifying key bacteria like Staphylococcus aureus and Enterococcus faecalis.
Area of Science:
- Microbiology
- Wound Healing
- Infectious Diseases
Background:
- Chronic wound infection significantly impedes healing.
- Diabetic foot syndrome presents a high incidence of infection, up to 30%.
- Accurate diagnosis and microbiological testing are vital for effective treatment.
Purpose of the Study:
- To conduct a comparative analysis of microbiota in infected chronic wounds.
- To analyze data from Polish outpatients at a wound care center (2013-2021).
Main Methods:
- Retrospective analysis of 3,917 microbiological test results from 1,199 patients.
- Microbiology cultures obtained via deep-tissue biopsy after wound debridement.
- Data categorized by microorganism type and incidence within different wound types.
Main Results:
- The most frequent isolates were Staphylococcus aureus (14.3% MRSA) and Enterococcus faecalis (2.4% VRE).
- Results presented as microorganism counts and relative incidence percentages.
- Identified prevalence of specific bacteria in infected chronic wounds.
Conclusions:
- Staphylococcus aureus and Enterococcus faecalis are prevalent in infected chronic wounds.
- Further analysis of antimicrobial susceptibility is needed.
- This data can inform new recommendations for empirical antibacterial treatment.
Related Concept Videos
01:20Infection
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
01:26Factors Affecting the Risk of Infection
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...