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Updated: Aug 4, 2025

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Pelvic radiation-induced urinary strictures: etiology and management of a challenging disease
Gregory Kunkel1, Hiren Patel2, Alain Kaldany2
1Department of Urology, UMass Chan: University of Massachusetts Medical School, Worcester, MA, USA. Gregory.Kunkel@umassmemorial.org.
Abstract:
Radiation is a common treatment modality for pelvic malignancies. While it can be effective at cancer control, downstream effects can manifest months to years after treatment, leaving patients with significant morbidity. Within urology, a particularly difficult post-radiation consequence is urinary tract stricture, either of the urethra, bladder neck, or ureter. In this review, we will discuss the mechanism of radiation damage and treatment options for these potentially devastating urinary sequelae.
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