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Related Experiment Video

Updated: Aug 4, 2025

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder

Published on: June 7, 2024

A Velocity-Based Approach to Noninvasive Methodology for Urodynamic Analysis.

Lorenzo Lotti¹, Pietro Spatafora^2,3, Vincenzo Li Marzi^2,3

¹Department of Civil and Environmental Engineering, University of Florence, Florence, Italy.

International Neurourology Journal

|April 4, 2023

Summary

This summary is machine-generated.

This study introduces a noninvasive method for diagnosing bladder conditions by measuring jet exit kinetic energy, replacing uncomfortable invasive urodynamic tests. This new approach shows high specificity in preliminary assessments.

Keywords:

Jet velocity Noninvasive methodology Urodynamics

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Last Updated: Aug 4, 2025

Author Spotlight: Enhanced Urodynamic Method for Precise Urine Measurement in Awake Mice with Neurogenic Bladder

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Published on: June 7, 2024

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing

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Published on: August 14, 2019

In Vivo Luminal Measurement of Distension-Evoked Urothelial ATP Release in Rodents

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Published on: September 7, 2022

Area of Science:

Urology
Biomedical Engineering
Medical Diagnostics

Background:

Lower urinary tract symptoms are typically diagnosed using invasive urodynamic investigations.
The discomfort associated with urethral catheterization is a major drawback of current diagnostic methods.

Purpose of the Study:

To investigate a noninvasive methodology for diagnosing bladder outlet obstruction or detrusor underactivity.
To eliminate patient discomfort associated with invasive urodynamic studies.

Main Methods:

Simultaneous measurement of flow rate and jet exit velocity.
Development of an experimental apparatus simulating the male lower urinary tract.
Collection of extensive data across different functional statuses.

Main Results:

Experimental results align with existing literature data for peak flow rate and jet exit velocity.
A novel diagram based on jet exit kinetic energy allows for noninvasive urodynamic studies.
Preliminary assessment in healthy men demonstrated 91.5% specificity.

Conclusions:

A noninvasive approach using jet exit kinetic energy measurement is proposed as an alternative to invasive urodynamic studies.
The proposed method shows promise for accurate diagnosis of lower urinary tract conditions.
Validation through comparison with pressure-flow studies confirms the approach's potential utility.