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Multimodal Optothermal Manipulations along Various Surfaces.

Hongru Ding1, Pavana Siddhartha Kollipara1, Kan Yao1,2

  • 1Walker Department of Mechanical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.

ACS Nano
|April 5, 2023
PubMed
Summary

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This study introduces an optothermal platform for precise multimodal manipulation of micro/nanoparticles. It enables five distinct working modes for versatile applications in life sciences and nanotechnology.

Area of Science:

  • Physics
  • Nanotechnology
  • Biophysics

Background:

  • Conventional optical tweezers offer contact-free manipulation but require complex systems for textured surfaces and are limited to single modes.
  • Applications like cell membrane characterization need precise micro/nanoparticle control on diverse surfaces.

Purpose of the Study:

  • To develop an optothermal platform for multimodal manipulation of micro/nanoparticles along various surfaces.
  • To overcome the limitations of conventional optical tweezers in terms of manipulation modes and surface adaptability.

Main Methods:

  • Utilizing a synergy between optical and thermal forces generated by laser-induced temperature gradients.
  • Implementing a simple laser beam control to achieve five switchable working modes: tweezing, rotating, rolling (toward/away), and shooting.
Keywords:
micro/nanoparticlesmultimodal manipulationoptical heatingoptical manipulationsingle-cell manipulation

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  • Demonstrating manipulation on synthesized particles, biological cells, and rough surfaces of live organisms.
  • Main Results:

    • Achieved multimodal manipulation of micro/nanoparticles with five distinct, switchable working modes.
    • Successfully manipulated both synthesized particles and biological cells on various substrates, including live worms and embryos.
    • Enabled three-dimensional control of micro/nano-objects on topologically uneven biological tissues.

    Conclusions:

    • The developed optothermal platform provides versatile, multimodal manipulation capabilities for micro/nanoparticles.
    • This technology offers precise control on diverse surfaces, including biological tissues, with potential applications in life sciences, nanotechnology, and colloidal sciences.
    • The platform overcomes limitations of conventional optical tweezers, enabling advanced research and applications.