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Clinical presentation of the first demyelinating event in pediatrics
Agustina Del Rosario Sbruzzi1, Salome Nasif2, Macarena Coloski3
1Hospital de Niños Pedro de Elizalde. sbruzziagustina@gmail.com.
Introduction:
Isolated Clinical Syndrome (ACS) refers to the first clinical event with characteristics suggestive of multiple sclerosis (MS).
Clinical Case:
We report the case of a previously healthy 8-year-old male patient hospitalized for altered gait with suspicion of transverse myelitis. Spinal MRI was performed showing evidence of hyperintense D3-D5 lesion in T2. He receives treatment with intravenous corticosteroid therapy and with the result of oligoclonal bands in serum and CSF, a diagnosis of ACS is made.
Conclusion:
The objective is to describe a rare form of manifestation of demyelinating disease in pediatric age and to assess the importance of timely diagnosis and treatment.
Insights
This case study presents a rare instance of first clinical event suggestive of multiple sclerosis (Acquired Clinical Syndrome or ACS) in an 8-year-old boy. Early diagnosis and treatment are crucial for managing this pediatric demyelinating disease.
Area of Science:
- Neurology
- Pediatric Neurology
- Neuroimmunology
Context:
- Acquired Clinical Syndrome (ACS) represents the initial clinical presentation suggestive of multiple sclerosis (MS).
- Pediatric demyelinating diseases require careful diagnostic consideration.
- Transverse myelitis can be an early sign of demyelinating conditions.
Purpose:
- To document a rare case of ACS in a pediatric patient.
- To highlight the diagnostic process for demyelinating diseases in children.
- To emphasize the significance of prompt diagnosis and treatment in pediatric ACS.
Summary:
- An 8-year-old male presented with altered gait, initially suspected as transverse myelitis.
- Spinal MRI revealed T2 hyperintense lesions at D3-D5.
- Diagnosis of ACS was confirmed by oligoclonal bands in serum and CSF, following corticosteroid treatment.
Impact:
- This case underscores the importance of recognizing ACS in pediatric populations.
- Timely intervention in pediatric demyelinating diseases can influence outcomes.
- Contributes to understanding rare neurological presentations in children.
