Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

499
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
499
Interactions Between Signaling Pathways01:19

Interactions Between Signaling Pathways

6.3K
Signaling cascades usually lack linearity. Multiple pathways interact and regulate one another, allowing cells to integrate and respond to diverse environmental stimuli.
Convergence and divergence, and cross-talk between signaling pathways
Two distinct signaling pathways can converge on a single functional unit, which may either be a single protein or a complex of proteins. The response is either functionally distinct or synergistic between the two pathways but different from the response...
6.3K
Correlation and Regression00:53

Correlation and Regression

1.4K
In statistics, correlation describes the degree of association between two variables. In the subfield of linear regression, correlation is mathematically expressed by the correlation coefficient, which describes the strength and direction of the relationship between two variables. The coefficient is symbolically represented by 'r' and ranges from -1 to +1. A positive value indicates a positive correlation where the two variables move in the same direction. A negative value suggests a...
1.4K
Contact-dependent Signaling01:19

Contact-dependent Signaling

44.8K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
44.8K
Correlation01:09

Correlation

12.2K
In statistics, two variables are said to be correlated if the values of one variable are associated with the other variable. Depending on the relationship between two variables, correlation can be of three types– positive correlation, negative correlation, and zero correlation.
Two variables, for example, a and b, are said to be positively correlated if both variables move in the same direction. In other words, a positive correlation exists between two variables, a and b, if:
12.2K
Affinity and Avidity01:41

Affinity and Avidity

36.4K
Overview
36.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diversity and expression pattern of novel macin genes in the earthworm, Eiseniaandrei.

Developmental and comparative immunology·2026
Same author

Identification and expression patterns of interleukin 17 (IL-17) genes in the earthworm Eisenia andrei: Differential inducibility and tissue-specific expression.

Journal of invertebrate pathology·2025
Same author

Unveiling salivary gland-specific gene expression of Piezo1 and Neuroendocrine in the leech, Helobdella austinensis.

Developmental and comparative immunology·2025
Same author

Hedgehog Signaling during Gut Formation in the Freshwater Leech, Helobdella austinensis.

Cells, tissues, organs·2025
Same author

Multiple diptericins of the black soldier fly (Hermetia illucens) differentially respond to bacterial challenges.

Journal of invertebrate pathology·2024
Same author

<i>Streptococcus suis</i> 5'-nucleotidases contribute to adenosine-mediated immune evasion and virulence in a mouse model.

Virulence·2024

Related Experiment Video

Updated: Aug 4, 2025

Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
03:31

Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

Published on: December 15, 2023

592

Interaction-and-Response Network for Distantly Supervised Relation Extraction.

Wei Song, Weishuai Gu, Fuxin Zhu

    IEEE Transactions on Neural Networks and Learning Systems
    |April 5, 2023
    PubMed
    Summary

    This study introduces the Interaction-and-Response Network (IR-Net) for distantly supervised relation extraction (DSRE). IR-Net improves entity relation extraction by modeling feature dependencies, outperforming existing methods.

    More Related Videos

    Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
    06:37

    Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

    Published on: December 15, 2023

    3.9K
    Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
    03:14

    Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

    Published on: December 6, 2024

    646

    Related Experiment Videos

    Last Updated: Aug 4, 2025

    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications
    03:31

    Author Spotlight: Enhancement of Salient Object Detection for Smart Grid Applications

    Published on: December 15, 2023

    592
    Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
    06:37

    Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

    Published on: December 15, 2023

    3.9K
    Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
    03:14

    Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

    Published on: December 6, 2024

    646

    Area of Science:

    • Natural Language Processing
    • Artificial Intelligence
    • Machine Learning

    Background:

    • Distantly supervised relation extraction (DSRE) identifies semantic relations in large text corpora.
    • Prior methods using selective attention neglect feature dependencies, hindering performance.
    • This limitation necessitates novel approaches for more effective relation extraction.

    Purpose of the Study:

    • To propose a new framework, the Interaction-and-Response Network (IR-Net), to address limitations in DSRE.
    • To adaptively recalibrate features at sentence, bag, and group levels by modeling interdependencies.
    • To enhance the learning of salient discriminative features for improved entity relation extraction.

    Main Methods:

    • Developed the Interaction-and-Response Network (IR-Net) framework.
    • Implemented interactive and responsive modules across feature hierarchies.
    • Explicitly modeled interdependencies among features at multiple levels.

    Main Results:

    • IR-Net demonstrated significant performance improvements on benchmark DSRE datasets (NYT-10, NYT-16, Wiki-20m).
    • The proposed method outperformed ten state-of-the-art DSRE techniques.
    • Modeling feature interdependencies proved crucial for enhancing extraction accuracy.

    Conclusions:

    • The IR-Net framework effectively captures feature dependencies, leading to superior DSRE performance.
    • Explicitly modeling interdependencies is a promising direction for advancing relation extraction.
    • IR-Net offers a robust solution for identifying semantic relations in massive text data.