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Normative data for macular perimetry using the MP-3 microperimeter in healthy individuals
Taurino Dos Santos Rodrigues Neto1, Epitácio Dias da Silva Neto1, Alex Haruo Higashi1
1Division of Ophthalmology, Laboratory for Investigation in Ophthalmology (LIM-33), Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Arquivos Brasileiros De Oftalmologia
|April 5, 2023
Summary
This study establishes normal microperimetry values using the MP-3 device in healthy individuals. It provides crucial baseline data for assessing retinal sensitivity and fixation stability, accounting for age-related changes.
Area of Science:
- Ophthalmology
- Visual Neuroscience
- Medical Imaging
Background:
- Microperimetry is vital for assessing visual function in retinal diseases.
- Establishing normal microperimetry values with the MP-3 is essential for accurate impairment assessment.
- Baseline data for macular sensitivity, age, and sex correlations are needed.
Purpose of the Study:
- Determine normal light sensitivity thresholds using the MP-3 microperimeter.
- Assess fixation stability in healthy individuals with the MP-3.
- Provide normative data for MP-3 microperimetry.
Main Methods:
- Full-threshold microperimetry with a 4-2 staircase strategy was used.
- Standard Goldmann III stimulus size and 68 test points (similar to Humphrey Field Analyzer 10-2) were employed.
- Fixation stability was recorded simultaneously, and age-related sensitivity decline was analyzed via linear regression.
Main Results:
- Global mean sensitivity was 29.01 ± 1.44 dB across 74 eyes of 37 healthy volunteers.
- Mean central sensitivity at 2° was 28.5 dB (OD) and 28.75 dB (OS).
- Age-related global sensitivity decline was observed (-0.051 dB/year OD, -0.078 dB/year OS).
Conclusions:
- MP-3 microperimetry offers automatic, accurate, and topography-specific retinal sensitivity testing.
- This study provides a normal, age-matched database for MP-3 microperimetry.
- The findings support MP-3 as a reliable tool for evaluating visual function.

