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Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain
Published on: August 8, 2019
Role of advanced MRI techniques for sacroiliitis assessment and quantification
Teodoro Martín-Noguerol1, Oscar L Casado-Verdugo2, Luis S Beltrán3
1MRI Unit, Radiology Department, HT Medica, Jaén, Spain.
Abstract:
The introduction of MRI was supposed to be a qualitative leap for the evaluation of Sacroiliac Joint (SIJ) in patients with Axial Spondyloarthropathies (AS). In fact, MRI findings such as bone marrow edema around the SIJ has been incorporated into the Assessment in SpondyloArthritis International Society (ASAS criteria). However, in the era of functional imaging, a qualitative approach to SIJ by means of conventional MRI seems insufficient. Advanced MRI sequences, which have successfully been applied in other anatomical areas, are demonstrating their potential utility for a more precise assessment of SIJ. Dixon sequences, T2-mapping, Diffusion Weighted Imaging or DCE-MRI can be properly acquired in the SIJ with promising and robust results. The main advantage of these sequences resides in their capability to provide quantifiable parameters that can be used for diagnosis of AS, surveillance or treatment follow-up. Further studies are needed to determine if these parameters can also be integrated into ASAS criteria for reaching a more precise classification of AS based not only on visual assessment of SIJ but also on measurable data.
Insights
Advanced MRI sequences offer quantifiable parameters for evaluating Sacroiliac Joint (SIJ) in Axial Spondyloarthropathies (AS), moving beyond qualitative assessment for better diagnosis and monitoring.
Area of Science:
- Radiology
- Rheumatology
- Medical Imaging
Background:
- Conventional MRI's qualitative assessment of Sacroiliac Joint (SIJ) in Axial Spondyloarthropathies (AS) is becoming insufficient.
- MRI findings like bone marrow edema are part of the Assessment in SpondyloArthritis International Society (ASAS) criteria.
Purpose of the Study:
- To explore the utility of advanced MRI sequences for a more precise assessment of the SIJ in AS patients.
- To evaluate the potential of quantifiable parameters from advanced MRI for AS diagnosis and management.
Main Methods:
- Application of advanced MRI sequences (Dixon, T2-mapping, DWI, DCE-MRI) to the SIJ.
- Acquisition of quantitative data from these advanced sequences.
Main Results:
- Advanced MRI sequences can be effectively acquired in the SIJ.
- These sequences yield promising and robust results with quantifiable parameters.
- The potential for improved diagnosis, surveillance, and treatment follow-up of AS is demonstrated.
Conclusions:
- Advanced MRI sequences offer a more precise, quantitative approach to SIJ assessment in AS.
- Further research is needed to integrate these quantitative parameters into ASAS criteria for improved AS classification.
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