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Enhancing Tumor Content through Tumor Macrodissection
Published on: February 12, 2022
[Primary effusion lymphoma-like lymphoma transformed to diffuse large B-cell lymphoma]
Naoto Ikeda1, Takeshi Imao1, Yuki Hisano1
1Department of Internal Medicine, Kaneda Hospital.
Abstract:
A rare kind of malignant lymphoma, called primary effusion lymphoma (PEL) is associated with human herpesvirus 8 (HHV-8), and characterized by lymphomatous effusion in the bodily cavities. Although the initial clinical presentation of primary effusion lymphoma-like lymphoma (PEL-LL) is similar to that of PEL, PEL-LL is HHV-8 negative and has a favorable prognosis. A PEL-LL diagnosis was made after an 88-year-old man was admitted to our hospital with a pleural effusion. His disease regressed after effusion drainage. He demonstrated disease progression to diffuse large B-cell lymphoma after two years and ten months. Our example demonstrates that aggressive B-cell lymphoma can develop from PEL-LL.
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