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Updated: Aug 4, 2025

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip
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Imaging-based intelligent spectrometer on a plasmonic rainbow chip.

Dylan Tua1, Ruiying Liu1, Wenhong Yang2

  • 1Electrical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, 14260, USA.

Nature Communications
|April 5, 2023
PubMed
Summary
This summary is machine-generated.

We developed a compact plasmonic "rainbow" chip for portable spectroscopic sensing. This device, using deep learning, accurately analyzes spectroscopic and polarimetric information from a single image, outperforming conventional portable spectrometers.

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Area of Science:

  • Nanophotonics and Plasmonics
  • Spectroscopic Sensing Technologies
  • Optical Engineering

Background:

  • Miniaturized spectrometers are crucial for portable sensing but often lack performance compared to lab instruments.
  • Oversimplified optical designs limit the capabilities of current compact spectrometers.
  • There is a need for high-performance, portable spectroscopic devices for in situ analysis.

Purpose of the Study:

  • To develop a compact, dual-functional plasmonic
  • rainbow
  • chip for enhanced spectroscopic and polarimetric sensing.
  • To demonstrate that this chip can surpass conventional portable spectrometers in specific applications.
  • To enable rapid and accurate analysis using a single image captured by an ordinary camera.

Main Methods:

  • Fabrication of one-dimensional or two-dimensional graded metallic gratings for the plasmonic chip.
  • Utilizing a single image from an ordinary camera to capture both spectroscopic and polarimetric data.
  • Employing deep learning algorithms for data analysis and characterization of optical rotatory dispersion.

Main Results:

  • The plasmonic
  • rainbow
  • chip successfully determined spectroscopic and polarimetric information from a single image.
  • Demonstrated accurate characterization of optical rotatory dispersion for glucose solutions across the visible spectrum.
  • Achieved performance exceeding conventional portable spectrometers under specific conditions.

Conclusions:

  • The developed compact plasmonic chip offers a powerful platform for rapid, accurate dual-functional sensing.
  • Integration with smartphones and lab-on-a-chip systems is feasible, enabling widespread in situ analysis.
  • This technology advances portable spectroscopic applications, moving beyond the limitations of current miniaturized devices.