Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pure Sertoli cell tumor of the right ovary managed with fertility-sparing surgery: a case report.

Oxford medical case reports·2026

Same author

Partial craniofacial duplication in a resource-limited setting: a case report.

International journal of surgery case reports·2026

Same author

Small bowel mesenteric cystic lymphangioma in an adult patient: a rare case report and review of literature.

International journal of surgery case reports·2026

Same author

Low-grade appendiceal mucinous neoplasm with heterotopic ossification and pseudomyxoma peritonei: a case report.

International journal of surgery case reports·2026

Same author

High grade non-Hodgkin lymphoma as culprit of ileal perforation in a patient presenting with generalized peritonitis: a case report.

Journal of medical case reports·2026

Same author

Cervical schistosomiasis masquerading as invasive carcinoma: a case report.

BMC infectious diseases·2025

Search research articles

Related Experiment Video

Updated: Aug 4, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Pediatric lymphatic leishmaniasis: a case report.

Endeshaw Asaye Kindie¹, Ermias Teklehaimanot Yefter², Bewketu Abebe Alemu²

¹Department of Pathology, University of Gondar College of Medicine and Health Sciences, Gondar, Ethiopia. endeshaw.asaye@uog.edu.et.

Journal of Medical Case Reports

|April 5, 2023

Summary

This case study highlights lymphatic leishmaniasis, a rare form of the disease presenting as isolated lymphadenopathy. Early consideration of leishmaniasis is crucial for timely diagnosis and treatment in endemic areas.

Keywords:

Leishmania donovani bodies Leishmaniasis Lymph node

More Related Videos

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase

Published on: April 4, 2025

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

Related Experiment Videos

Last Updated: Aug 4, 2025

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase

Published on: April 4, 2025

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

Published on: December 30, 2012

Area of Science:

Medical Parasitology
Infectious Diseases
Clinical Case Reports

Background:

Leishmaniasis presents in three main forms: visceral, cutaneous, and mucocutaneous, caused by protozoan parasites transmitted by sandflies.
The disease disproportionately affects impoverished populations and is linked to factors like malnutrition and compromised immunity.
An estimated 700,000 to 1 million new cases occur annually, though only a fraction of infected individuals develop the disease.

Observation:

A 12-year-old male in Ethiopia presented with exclusive lymph node involvement, characterized by localized cervical lymphadenopathies without skin lesions.
Fine needle aspiration cytology confirmed Leishmania donovani in the lymph node, supported by positive anti-rK39 antibodies.
Bone marrow aspiration and abdominal ultrasound ruled out disseminated visceral leishmaniasis or organomegaly.

Findings:

The case demonstrates lymphatic leishmaniasis with exclusive lymph node involvement, a rare presentation.
Diagnosis was confirmed via lymph node cytology and serology, despite negative bone marrow findings.
The patient received a 17-day course of sodium stibogluconate and paromomycin injections.

Implications:

Localized lymphadenopathies can mimic other conditions like lymphoma, posing a diagnostic challenge.
Leishmaniasis should be considered in the differential diagnosis of isolated lymphadenopathies in immunocompetent individuals in endemic regions.
Early diagnostic workup and prompt management are essential for favorable outcomes in lymphatic leishmaniasis.