Electrophysiological study as a predictor of mortality in unexplained syncope

Area of Science:

• Cardiology
• Electrophysiology
• Clinical Research

Background:

• Electrophysiological study (EPS) aids in diagnosing syncope.
• Prognostic implications of EPS findings in syncope patients require further investigation.

Purpose of the Study:

• To evaluate syncope patient survival based on EPS findings.
• To identify independent clinical and electrophysiological predictors of all-cause mortality.

Main Methods:

• Retrospective cohort study of 383 syncope patients undergoing EPS (2009-2018).
• Cox logistic regression analysis to determine prognostic factors for mortality.

Main Results:

• The split His group exhibited the poorest survival, followed by sustained ventricular tachycardia and HV interval ≥ 70 ms.
• Age, congestive heart failure, split His, and sustained ventricular tachycardia were identified as independent predictors of all-cause mortality.

Conclusions:

• Patients with split His, sustained ventricular tachycardia, or HV interval ≥ 70 ms showed reduced survival.
• Key mortality predictors include age, congestive heart failure, split His, and sustained ventricular tachycardia.