CFD analysis of the hyper-viscous effects on blood flow across abdominal aortic aneurysm in COVID patients:

Shankar Narayan S1,2, Anuradha Bhattacharjee2, Sunanda Saha3

  • 1Department of Mathematics and Statistics, Ramaiah University of Applied Sciences, Bengaluru, India.

Insights

COVID-19 infection increases blood viscosity, potentially worsening abdominal aortic aneurysms. This study models hyperviscous blood flow in aneurysms, revealing increased wall stress that may accelerate enlargement or rupture.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Fluid Mechanics

Background:

  • COVID-19 is linked to elevated blood viscosity due to cellular changes.
  • Blood hyperviscosity significantly impacts hemodynamics, particularly in arterial pathologies like aneurysms.
  • Abdominal aortic aneurysms are a prevalent and often fatal condition.

Purpose of the Study:

  • To investigate the hemodynamic effects of COVID-19-induced hyperviscosity on abdominal aortic aneurysms.
  • To analyze blood flow patterns in patient-specific aneurysms considering elastic vessel walls.
  • To evaluate the influence of elevated blood viscosity on aneurysm progression and rupture risk.

Main Methods:

  • Utilized a patient-specific computational fluid dynamics (CFD) model.
  • Employed the arbitrary Lagrangian-Eulerian (ALE) approach to handle fluid-structure interaction.
  • Solved coupled fluid and solid mechanics equations using a Finite Element Method (FEM) solver.

Main Results:

  • Simulations demonstrated increased wall shear stress in aneurysms with hyperviscous blood flow.
  • The elastic nature of the aortic wall was incorporated into the flow analysis.
  • Findings align with clinical observations of detrimental effects of blood hyperviscosity.

Conclusions:

  • Elevated blood viscosity in COVID-19 patients can significantly increase stress on aneurysm walls.
  • This increased stress may accelerate the expansion of abdominal aortic aneurysms.
  • The study highlights the critical role of blood rheology in aneurysm pathophysiology and rupture risk.